TOX4 and TBX6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		TOX4	TBX6
Description		TOX high mobility group box family member 4	T-box transcription factor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Chromatin PTW/PP1 Phosphatase Complex	Nuclear Chromatin Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Vasculogenesis Mesoderm Formation Cell Fate Specification Heart Looping Mesoderm Development Anatomical Structure Morphogenesis Negative Regulation Of Neuron Projection Development Negative Regulation Of Neuron Maturation Signal Transduction Involved In Regulation Of Gene Expression Somite Rostral/caudal Axis Specification Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Eosinophil counts ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244) Red blood cell count ( 29403010 27863252) Schizophrenia ( 25056061 29483656) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		15 interacting genes: ATXN1 BANP CCBE1 CREB1 EXOSC10 FNDC3B GEMIN6 HIPK3 HSPB1 MYL7 PPP1CA TBX6 WDR82 ZMYND19 ZNF512B	7 interacting genes: C1orf94 HSFY1 MEOX2 PRMT1 PSMA3 RBPMS TOX4
Entrez ID		9878	6911
HPRD ID		12661	03888
Ensembl ID		ENSG00000092203	ENSG00000149922
Uniprot IDs		O94842	O95947
PDB IDs
Enriched GO Terms of Interacting Partners?
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