TBX6 and TOX4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		TBX6	TOX4
Description		T-box transcription factor 6	TOX high mobility group box family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nuclear Chromosome, Telomeric Region Chromatin PTW/PP1 Phosphatase Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Vasculogenesis Mesoderm Formation Cell Fate Specification Heart Looping Mesoderm Development Anatomical Structure Morphogenesis Negative Regulation Of Neuron Projection Development Negative Regulation Of Neuron Maturation Signal Transduction Involved In Regulation Of Gene Expression Somite Rostral/caudal Axis Specification Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Eosinophil counts ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244) Red blood cell count ( 29403010 27863252) Schizophrenia ( 25056061 29483656) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		7 interacting genes: C1orf94 HSFY1 MEOX2 PRMT1 PSMA3 RBPMS TOX4	15 interacting genes: ATXN1 BANP CCBE1 CREB1 EXOSC10 FNDC3B GEMIN6 HIPK3 HSPB1 MYL7 PPP1CA TBX6 WDR82 ZMYND19 ZNF512B
Entrez ID		6911	9878
HPRD ID		03888	12661
Ensembl ID		ENSG00000149922	ENSG00000092203
Uniprot IDs		O95947	O94842
PDB IDs
Enriched GO Terms of Interacting Partners?
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