TBX6 and C1orf94

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		TBX6	C1orf94
Description		T-box transcription factor 6	chromosome 1 open reading frame 94
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Vasculogenesis Mesoderm Formation Cell Fate Specification Heart Looping Mesoderm Development Anatomical Structure Morphogenesis Negative Regulation Of Neuron Projection Development Negative Regulation Of Neuron Maturation Signal Transduction Involved In Regulation Of Gene Expression Somite Rostral/caudal Axis Specification Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Eosinophil counts ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244) Red blood cell count ( 29403010 27863252) Schizophrenia ( 25056061 29483656) Sum eosinophil basophil counts ( 27863252)	Generalized epilepsy ( 22949513) Lateral ventricle temporal horn volume ( 31530798) Pediatric nonalcoholic steatohepatitis ( 28918882) Sleep duration (short sleep) ( 30846698)
Interacting Genes		7 interacting genes: C1orf94 HSFY1 MEOX2 PRMT1 PSMA3 RBPMS TOX4	66 interacting genes: ACTN3 AKAP9 ATRIP ATXN1 BANP BOLA1 BOLL BYSL C1orf109 CARD9 CCHCR1 CCNJL CDKN2D CFAP206 CLK1 CRK CRYBA4 DAB1 DAZAP2 DGCR6 DMRTB1 DOK6 DTX2 FAM168A GCC1 GORASP2 GRB2 GSE1 HGS HNRNPF IPO11 KLHL32 LMO2 MAGED1 MAPK1IP1L MAPK9 MEIS2 MVP NFKBID NGB NR3C1 OAZ3 OIP5 PITX1 PLEKHB2 PRKAG1 PRR20A R3HDM2 RAD51D RBFOX1 RBFOX2 RBM47 RBPMS RFX2 ROR2 SMAP2 TBX6 TENT5D TLE5 TNPO2 TXNDC9 UBQLN4 USO1 VENTX VPS37C YES1
Entrez ID		6911	84970
HPRD ID		03888	11310
Ensembl ID		ENSG00000149922	ENSG00000142698
Uniprot IDs		O95947	Q6P1W5
PDB IDs
Enriched GO Terms of Interacting Partners?
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