RB1CC1 and IL13RA2

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		RB1CC1	IL13RA2
Description		RB1 inducible coiled-coil 1	interleukin 13 receptor subunit alpha 2
Image
GO Annotations	Cellular Component	Phagophore Assembly Site Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex	Extracellular Region Extracellular Space External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function	Protein Binding Protein Kinase Binding Molecular Adaptor Activity	Cytokine Receptor Activity Protein Binding Cytokine Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Negative Regulation Of Immunoglobulin Production Immunoglobulin Mediated Immune Response Cytokine-mediated Signaling Pathway Negative Regulation Of Mast Cell Degranulation
Pathways		Macroautophagy	Interleukin-4 and Interleukin-13 signaling
Drugs			AER001
Diseases
GWAS		Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		36 interacting genes: ATG13 BAP1 BLID CALCOCO2 COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MAP1LC3A MAP1LC3B MAP1LC3C MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1	15 interacting genes: AKT1 BAG4 BRMS1 CASP8 EGFR ERBB2 ESR2 IGF1R IL13 IL4 NOTCH2 PALB2 PAX2 PIK3CA RB1CC1
Entrez ID		9821	3598
HPRD ID		06019	02132
Ensembl ID		ENSG00000023287	ENSG00000123496
Uniprot IDs		Q8TDY2	Q14627
PDB IDs		6DCE 6GMA	3LB6
Enriched GO Terms of Interacting Partners?
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