RB1CC1 and ATG13

Number of citations of the paper that reports this interaction (PubMedID 20562859)
598

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		RB1CC1	ATG13
Description		RB1 inducible coiled-coil 1	autophagy related 13
Image
GO Annotations	Cellular Component	Phagophore Assembly Site Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex	Phagophore Assembly Site Mitochondrion Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Protein Binding Protein Kinase Binding Molecular Adaptor Activity	Protein Binding Protein Kinase Regulator Activity Protein Kinase Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Macroautophagy Regulation Of Macroautophagy Activation Of Protein Kinase Activity Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Autophagy Of Nucleus Response To Mitochondrial Depolarisation Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		Macroautophagy	Macroautophagy
Drugs
Diseases
GWAS		Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Waist circumference adjusted for body mass index ( 28552196)	Age at first sexual intercourse ( 27089180) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Headache ( 29397368) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 29483656) Selective IgA deficiency ( 27723758)
Interacting Genes		36 interacting genes: ATG13 BAP1 BLID CALCOCO2 COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MAP1LC3A MAP1LC3B MAP1LC3C MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1	12 interacting genes: APP ATG101 ATG14 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C RB1CC1 SMCR8 ULK1
Entrez ID		9821	9776
HPRD ID		06019	13809
Ensembl ID		ENSG00000023287	ENSG00000175224
Uniprot IDs		Q8TDY2	A8K0S6 O75143
PDB IDs		6DCE 6GMA	3WAN 3WAO 3WAP 5C50 5XUY 5XV1 5XV3 5XV4 5XV6 6HYN
Enriched GO Terms of Interacting Partners?
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