KEAP1 and FAM117B

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 381
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

KEAP1

FAM117B

Description kelch like ECH associated protein 1 family with sequence similarity 117 member B
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index and waist-hip ratio (pleiotropy) ( 29868124)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908)
Interacting Genes 49 interacting genes: AK4 AMER1 ATG5 BAD BPTF CAT CCNB1IP1 CDH1 CDK6 CLU CPEB2 CTTN CUL3 EGFR ETF1 FAM117B GLRX5 GYPA HSP90AA1 HSP90AB1 IPO11 IRF1 KLHL3 KPNA6 LSM3 MAD2L1 MAPKBP1 MYO7A NFE2L2 NUDT4 OXR1 PDCD6IP PIDD1 PPP1R13L PRKAG1 PTMA RAF1 RECK RELA SNRPN STK3 STK4 TENT5A TERF1 TRIM15 UBC USP15 WDR83 ZSCAN32 3 interacting genes: BANP KEAP1 STAT3
Entrez ID 9817 150864
HPRD ID 12079 12445
Ensembl ID ENSG00000079999 ENSG00000138439
Uniprot IDs A0A024R7C0 Q14145 Q6P1L5 Q7Z3M2
PDB IDs 1U6D 1ZGK 2FLU 3VNG 3VNH 3ZGC 3ZGD 4CXI 4CXJ 4CXT 4IFJ 4IFL 4IFN 4IN4 4IQK 4L7B 4L7C 4L7D 4N1B 4XMB 5DAD 5DAF 5F72 5GIT 5NLB 5WFL 5WFV 5WG1 5WHL 5WHO 5WIY 5X54 6FFM 6FMP 6FMQ 6HWS 6ROG
Enriched GO Terms of Interacting Partners?
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