TRAF4 and MRPL28

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRAF4	MRPL28
Description		TNF receptor associated factor 4	mitochondrial ribosomal protein L28
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Plasma Membrane Bicellular Tight Junction Perinuclear Region Of Cytoplasm Plasma Membrane Receptor Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Cytosol
	Molecular Function	Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding WW Domain Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Apoptotic Process Activation Of NF-kappaB-inducing Kinase Activity Respiratory Gaseous Exchange Respiratory Tube Development Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Protein K63-linked Ubiquitination	Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS			Body mass index ( 26426971) Heel bone mineral density ( 28869591)
Interacting Genes		78 interacting genes: ALKBH4 BAHD1 BANP BCKDK BCL6B BEX3 BYSL CALCOCO2 CBL CBLC CCHCR1 CENPE CHUK DTX3 EXOC7 FAM214B FAM90A1 FAT1 FBXL18 FTH1 GOLGA2 GORASP2 GPRASP1 HGS HOMEZ IRAK1 ISYNA1 KANSL1 KDM1A KRT31 KRT40 LTBR MAGEC2 MAGED1 MAP3K4 MRPL28 NCF1 NGFR NOS1AP NPAS2 NTRK1 PDE4DIP PKD1P1 PLSCR1 PSMC3 QARS1 RBPMS REXO1L6P RNF114 RPS6KB1 SIGLEC7 SMURF1 SMURF2 SORBS2 SPDL1 SUMO1 TARBP2 TBC1D7 TBC1D8 TGFB1I1 TICAM1 TNFRSF4 TP53BP2 TRAF6 TRIM37 TYK2 UBE2D1 UBE2I UBL4A UBL4B USP7 WBP11 WWP1 WWP2 ZNF3 ZNF512B ZNF581 ZNF688	14 interacting genes: APP BANP CDR2 FAM9B HMBOX1 HSPB1 HTR2A IKZF3 LRRK2 OXA1L TEF TRAF3IP2 TRAF4 TUBB3
Entrez ID		9618	10573
HPRD ID		03915	06889
Ensembl ID		ENSG00000076604	ENSG00000086504
Uniprot IDs		A0A024QZ19 A0A024QZ59 Q9BUZ4	Q13084
PDB IDs		2EOD 2YUC 3ZJB 4K8U 4M4E 5YC1	3J7Y 5OOL 5OOM 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
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