PRDX6 and STH

Number of citations of the paper that reports this interaction (PubMedID 16186110)
9

Data Source:
BioGRID (two hybrid)

		PRDX6	STH
Description		peroxiredoxin 6	saitohin
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Nucleus Cytoplasm Mitochondrion Cytosol Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Glutathione Peroxidase Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Cadherin Binding Calcium-independent Phospholipase A2 Activity Peroxiredoxin Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)	Protein Binding
	Biological Process	Response To Oxidative Stress Cellular Response To Oxidative Stress Hydrogen Peroxide Catabolic Process Neutrophil Degranulation Cell Redox Homeostasis Glycerophospholipid Catabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Oxidation-reduction Process Cellular Oxidant Detoxification	Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Detoxification of Reactive Oxygen Species Neutrophil degranulation
Drugs		Isopropyl Alcohol 2-(N-Morpholino)-Ethanesulfonic Acid Copper
Diseases
GWAS		Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Blood protein levels ( 30072576) Systemic lupus erythematosus ( 26663301) Systemic sclerosis ( 31672989)	Alcohol consumption ( 31358974) Alcohol use disorder (total score) ( 30336701) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Idiopathic pulmonary fibrosis ( 24429156) Intracranial volume ( 22504418) Male-pattern baldness ( 28196072) Neurociticism ( 29500382) Neuroticism ( 29255261) Number of sexual partners ( 30643258) Parkinson's disease ( 28892059 22438815) Risk-taking tendency (4-domain principal component model) ( 30643258) Sleep duration ( 30531941) Subcortical brain region volumes ( 25607358)
Interacting Genes		19 interacting genes: CASP10 CASP8 GPX4 GSTP1 HNF4G MAPK1 NCF2 NR4A1 ORM2 PAXIP1 PPARD RARA SFTPA1 STH SUMO4 TERF1 TERF2IP UCHL5 YWHAE	1 interacting genes: PRDX6
Entrez ID		9588	246744
HPRD ID		03817	06142
Ensembl ID		ENSG00000117592	ENSG00000256762
Uniprot IDs		P30041 V9HWC7	Q8IWL8
PDB IDs		1PRX 5B6M 5B6N
Enriched GO Terms of Interacting Partners?
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