PRDX6

Description		peroxiredoxin 6
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Nucleus Cytoplasm Mitochondrion Cytosol Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Glutathione Peroxidase Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Cadherin Binding Calcium-independent Phospholipase A2 Activity Peroxiredoxin Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
	Biological Process	Response To Oxidative Stress Cellular Response To Oxidative Stress Hydrogen Peroxide Catabolic Process Neutrophil Degranulation Cell Redox Homeostasis Glycerophospholipid Catabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Oxidation-reduction Process Cellular Oxidant Detoxification
Pathways		Detoxification of Reactive Oxygen Species Neutrophil degranulation
Drugs		Isopropyl Alcohol 2-(N-Morpholino)-Ethanesulfonic Acid Copper
Diseases
GWAS		Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Blood protein levels ( 30072576) Systemic lupus erythematosus ( 26663301) Systemic sclerosis ( 31672989)
Interacting Genes		19 interacting genes: CASP10 CASP8 GPX4 GSTP1 HNF4G MAPK1 NCF2 NR4A1 ORM2 PAXIP1 PPARD RARA SFTPA1 STH SUMO4 TERF1 TERF2IP UCHL5 YWHAE
Entrez ID		9588
HPRD ID		03817
Ensembl ID		ENSG00000117592
Uniprot IDs		P30041 V9HWC7
PDB IDs		1PRX 5B6M 5B6N
Enriched GO Terms of Interacting Partners?
Tagcloud ?