BAG3 and FAM189A2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		BAG3	FAM189A2
Description		BAG cochaperone 3	family with sequence similarity 189 member A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cell Nucleus Cytoplasm Cytosol Plasma Membrane Aggresome Z Disc Neuron Projection Chaperone Complex	Cellular_component Integral Component Of Membrane
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein-containing Complex Binding Cadherin Binding Dynein Intermediate Chain Binding Chaperone Binding	Molecular_function
	Biological Process	Autophagosome Assembly Protein Folding Brain Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Striated Muscle Cell Apoptotic Process Spinal Cord Development Cellular Response To Heat Cellular Response To Unfolded Protein Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Apoptotic Process Muscle Cell Cellular Homeostasis Positive Regulation Of Protein Export From Nucleus Regulation Of Catalytic Activity Protein Stabilization Chaperone-mediated Autophagy Aggresome Assembly Cellular Response To Mechanical Stimulus Chaperone-mediated Protein Transport Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Protein Transport Along Microtubule Regulation Of Cellular Response To Heat Negative Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Aggrephagy	Biological_process
Pathways		Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Heart failure ( 31919418) Idiopathic dilated cardiomyopathy ( 21459883) Parkinson's disease ( 27182965 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Coronary artery disease in type 1 diabetes ( 29695241)
Interacting Genes		25 interacting genes: ACD ARRDC3 BCL2 CRYAB DAZAP2 DVL2 DYNLT1 FAM189A2 FBXO7 HSPA1A HSPA8 HSPB1 HSPB8 LITAF LRRK1 LRRK2 MAGED1 PDE9A PLCG1 POT1 SF3B4 SRPK2 TINF2 TNK2 WNK1	10 interacting genes: BAG3 CALCOCO2 OPTN SFN STAM2 TAX1BP1 UBQLN1 UBXN1 WWP1 WWP2
Entrez ID		9531	9413
HPRD ID		04860	16255
Ensembl ID		ENSG00000151929	ENSG00000135063
Uniprot IDs		O95817	A0A0A0MR12 Q15884 Q8WU02
PDB IDs
Enriched GO Terms of Interacting Partners?
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