RPH3AL and UNC13B

Number of citations of the paper that reports this interaction (PubMedID 14593078)
16

Data Source:
HPRD (in vitro)

		RPH3AL	UNC13B
Description		rabphilin 3A like (without C2 domains)	unc-13 homolog B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane	Cell Golgi Apparatus Cytosol Plasma Membrane Membrane Cell Junction Synaptic Vesicle Membrane Neuromuscular Junction Early Phagosome Presynaptic Membrane Terminal Bouton Calyx Of Held Presynaptic Active Zone Ribbon Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Rab GTPase Binding LIM Domain Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Calmodulin Binding Phospholipid Binding Syntaxin-1 Binding Rab GTPase Binding Diacylglycerol Binding GTP-dependent Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Insulin Secretion Response To Drug Glucose Homeostasis Negative Regulation Of G Protein-coupled Receptor Signaling Pathway	Chemical Synaptic Transmission Neurotransmitter Secretion Neuromuscular Junction Development Positive Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Maturation Negative Regulation Of Synaptic Plasticity Synaptic Transmission, Glutamatergic Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Protein Secretion Innervation Acrosomal Vesicle Exocytosis Dense Core Granule Priming Cellular Response To Glucose Stimulus Phagosome Maturation Positive Regulation Of Inhibitory Postsynaptic Potential Neuronal Dense Core Vesicle Exocytosis Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Defense Response To Bacterium
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		AIDS progression ( 21502085) Dimensional psychopathology (Cognitive) ( 29496196) Idiopathic intracranial hypertension ( 29608535) Impaired insulin sensitivity in response to n-3 PUFA supplementation ( 31779001)	Parkinson's disease ( 21812969)
Interacting Genes		13 interacting genes: MID2 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 TCEA3 UNC13B ZYX	10 interacting genes: CLK1 DOC2A DOC2B RIMS1 RPH3AL SPTBN2 STX1A STX1B STX2 TOE1
Entrez ID		9501	10497
HPRD ID		05345	05785
Ensembl ID		ENSG00000181031	ENSG00000198722
Uniprot IDs		A8K7D5 Q9UNE2	O14795 Q4LE73
PDB IDs
Enriched GO Terms of Interacting Partners?
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