UNC13B and STX1B

Number of citations of the paper that reports this interaction (PubMedID 8999968)
90

Data Source:
BioGRID (two hybrid, biochemical)

		UNC13B	STX1B
Description		unc-13 homolog B	syntaxin 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Golgi Apparatus Cytosol Plasma Membrane Membrane Cell Junction Synaptic Vesicle Membrane Neuromuscular Junction Early Phagosome Presynaptic Membrane Terminal Bouton Calyx Of Held Presynaptic Active Zone Ribbon Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse	Nucleus Microtubule Organizing Center Spindle Cytosol Plasma Membrane Endomembrane System Membrane Integral Component Of Membrane Axon SNARE Complex Neuromuscular Junction Presynaptic Active Zone Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Calmodulin Binding Phospholipid Binding Syntaxin-1 Binding Rab GTPase Binding Diacylglycerol Binding GTP-dependent Protein Binding	SNARE Binding Signaling Receptor Binding SNAP Receptor Activity Protein Kinase Binding Protein Domain Specific Binding
	Biological Process	Chemical Synaptic Transmission Neurotransmitter Secretion Neuromuscular Junction Development Positive Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Maturation Negative Regulation Of Synaptic Plasticity Synaptic Transmission, Glutamatergic Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Protein Secretion Innervation Acrosomal Vesicle Exocytosis Dense Core Granule Priming Cellular Response To Glucose Stimulus Phagosome Maturation Positive Regulation Of Inhibitory Postsynaptic Potential Neuronal Dense Core Vesicle Exocytosis Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Defense Response To Bacterium	Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Negative Regulation Of Neuron Projection Development Synaptic Vesicle Docking Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Activity Spontaneous Neurotransmitter Secretion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Negative Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle	Toxicity of botulinum toxin type C (BoNT/C) LGI-ADAM interactions
Drugs
Diseases
GWAS		Parkinson's disease ( 21812969)	Body mass index ( 31453325) Body mass index variance ( 31453325) Dementia with Lewy bodies ( 29263008) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Juvenile myoclonic epilepsy ( 30531953) Parkinson's disease ( 25064009) Psoriasis ( 25574825) Response to metformin (IC50) ( 28173075) Waist circumference ( 31453325) Waist circumference variance ( 31453325)
Interacting Genes		10 interacting genes: CLK1 DOC2A DOC2B RIMS1 RPH3AL SPTBN2 STX1A STX1B STX2 TOE1	6 interacting genes: NPTX1 SNAP23 STXBP1 UNC13B VAMP1 VAMP2
Entrez ID		10497	112755
HPRD ID		05785	18126
Ensembl ID		ENSG00000198722	ENSG00000099365
Uniprot IDs		O14795 Q4LE73	P61266
PDB IDs
Enriched GO Terms of Interacting Partners?
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