UNC13B and TOE1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		UNC13B	TOE1
Description		unc-13 homolog B	target of EGR1, exonuclease
Image		No pdb structure
GO Annotations	Cellular Component	Cell Golgi Apparatus Cytosol Plasma Membrane Membrane Cell Junction Synaptic Vesicle Membrane Neuromuscular Junction Early Phagosome Presynaptic Membrane Terminal Bouton Calyx Of Held Presynaptic Active Zone Ribbon Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse	Nucleoplasm Nucleolus Cytoplasm Cajal Body Nuclear Body Nuclear Speck
	Molecular Function	Calcium Ion Binding Protein Binding Calmodulin Binding Phospholipid Binding Syntaxin-1 Binding Rab GTPase Binding Diacylglycerol Binding GTP-dependent Protein Binding	3'-5'-exoribonuclease Activity RNA Binding Poly(A)-specific Ribonuclease Activity Protein Binding SnRNA Binding Metal Ion Binding
	Biological Process	Chemical Synaptic Transmission Neurotransmitter Secretion Neuromuscular Junction Development Positive Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Maturation Negative Regulation Of Synaptic Plasticity Synaptic Transmission, Glutamatergic Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Protein Secretion Innervation Acrosomal Vesicle Exocytosis Dense Core Granule Priming Cellular Response To Glucose Stimulus Phagosome Maturation Positive Regulation Of Inhibitory Postsynaptic Potential Neuronal Dense Core Vesicle Exocytosis Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Defense Response To Bacterium	SnRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		Parkinson's disease ( 21812969)
Interacting Genes		10 interacting genes: CLK1 DOC2A DOC2B RIMS1 RPH3AL SPTBN2 STX1A STX1B STX2 TOE1	25 interacting genes: ABCF3 AGGF1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83
Entrez ID		10497	114034
HPRD ID		05785	18212
Ensembl ID		ENSG00000198722	ENSG00000132773
Uniprot IDs		O14795 Q4LE73	Q96GM8
PDB IDs			2FC6
Enriched GO Terms of Interacting Partners?
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