MYOT and GPRASP2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		MYOT	GPRASP2
Description		myotilin	G protein-coupled receptor associated sorting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Actin Cytoskeleton Z Disc Axon Sarcolemma Neuronal Cell Body	Nucleus Cytoplasm
	Molecular Function	Actin Binding Protein Binding Axon Guidance Receptor Activity Structural Constituent Of Muscle Alpha-actinin Binding	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding
	Biological Process	Muscle Contraction Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Synapse Organization
Pathways
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy Limb-girdle muscular dystrophy (LGMD)
GWAS		Atrial fibrillation ( 30061737) Heart rate ( 23583979) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699)
Interacting Genes		13 interacting genes: ACTN1 ACTN2 APP AXIN1 FLNA FLNC GPRASP2 LRP12 NME7 ST7 TFG TRIM55 TRIM63	29 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CBX8 CEP126 CFAP206 CHRM1 CHRM2 DISC1 FRAT1 HAP1 HRH2 HTR7 HTT LRIF1 MICU2 MYOT NOL4L-DT PRPF3 PTN RPS6KA5 RTL10 STMN2 TCF25 TSPOAP1 TXN TXN2 ZNF688
Entrez ID		9499	114928
HPRD ID		04981	06612
Ensembl ID		ENSG00000120729	ENSG00000158301
Uniprot IDs		A0A0C4DFM5 B4DT68 Q9UBF9	B3KW05 Q96D09
PDB IDs		2KDG 2KKQ
Enriched GO Terms of Interacting Partners?
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