MYOT and TFG

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		MYOT	TFG
Description		myotilin	trafficking from ER to golgi regulator
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Actin Cytoskeleton Z Disc Axon Sarcolemma Neuronal Cell Body	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site
	Molecular Function	Actin Binding Protein Binding Axon Guidance Receptor Activity Structural Constituent Of Muscle Alpha-actinin Binding	Protein Binding Identical Protein Binding
	Biological Process	Muscle Contraction Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Synapse Organization	ER To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating
Pathways			COPII-mediated vesicle transport
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy Limb-girdle muscular dystrophy (LGMD)	Non-small cell lung cancer Thyroid cancer
GWAS		Atrial fibrillation ( 30061737) Heart rate ( 23583979) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699)
Interacting Genes		13 interacting genes: ACTN1 ACTN2 APP AXIN1 FLNA FLNC GPRASP2 LRP12 NME7 ST7 TFG TRIM55 TRIM63	32 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL CEP126 CEP55 CRMP1 CSTF2 ERG28 EWSR1 GBP2 GPRASP1 GRB2 HGS HNRNPF MAGED1 MAPK1IP1L MED21 MYOT PEF1 PIN1 PLSCR1 PTPN6 RBPMS RIPPLY2 SEC24A SPG21 STAT5B TOMM70 TRIM25 TSSK2 VPS37C
Entrez ID		9499	10342
HPRD ID		04981	03932
Ensembl ID		ENSG00000120729	ENSG00000114354
Uniprot IDs		A0A0C4DFM5 B4DT68 Q9UBF9	Q05BK6 Q92734
PDB IDs		2KDG 2KKQ
Enriched GO Terms of Interacting Partners?
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