GPRASP2 and CHRM1

Number of citations of the paper that reports this interaction (PubMedID 15086532)
34

Data Source:
HPRD (in vitro)

		GPRASP2	CHRM1
Description		G protein-coupled receptor associated sorting protein 2	cholinergic receptor muscarinic 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Membrane Cell Junction Dendrite Axon Terminus Synapse Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Cholinergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process		Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Neuromuscular Synaptic Transmission Nervous System Development Regulation Of Locomotion Positive Regulation Of Ion Transport Saliva Secretion Cognition Regulation Of Postsynaptic Membrane Potential Regulation Of Glial Cell Proliferation Positive Regulation Of Intracellular Protein Transport G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Muscarinic acetylcholine receptors G alpha (q) signalling events
Drugs			Cevimeline Succinylcholine Trospium Citalopram Oxyphenonium Benzatropine Ziprasidone Disopyramide Amitriptyline Ipratropium bromide Olanzapine Metixene Terfenadine Buclizine Clozapine Doxylamine Trihexyphenidyl Oxyphencyclimine Procyclidine Ethopropazine Loxapine Carbachol Promazine Hyoscyamine Cyproheptadine Pethidine Imipramine Methylscopolamine bromide Chlorpromazine Gallamine Triethiodide Darifenacin Tridihexethyl Triflupromazine Anisotropine Methylbromide Nortriptyline Amoxapine Amoxapine Cinnarizine Atropine Nicardipine Pirenzepine Paroxetine Homatropine Methylbromide Trimipramine Scopolamine Benzquinamide Clidinium Propiomazine Propantheline Cryptenamine Dicyclomine Minaprine Tropicamide Biperiden Brompheniramine Flupentixol Cocaine Maprotiline Methantheline Cycrimine Cyclopentolate Glycopyrronium Bethanechol Tolterodine Oxybutynin Promethazine Pilocarpine Doxepin Flavoxate Desipramine Escitalopram Ketamine Quetiapine Diphenidol Metoclopramide Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin Molindone Staurosporine Acetylcholine Arecoline Mepenzolate NGX267 ALKS 27 ACP-104 Fesoterodine Hexocyclium Aclidinium Umeclidinium Dosulepin Etoperidone Imidafenacin
Diseases
GWAS			Urate levels ( 31578528)
Interacting Genes		29 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CBX8 CEP126 CFAP206 CHRM1 CHRM2 DISC1 FRAT1 HAP1 HRH2 HTR7 HTT LRIF1 MICU2 MYOT NOL4L-DT PRPF3 PTN RPS6KA5 RTL10 STMN2 TCF25 TSPOAP1 TXN TXN2 ZNF688	5 interacting genes: CDC14A GNAI2 GPRASP1 GPRASP2 RGS7
Entrez ID		114928	1128
HPRD ID		06612	00338
Ensembl ID		ENSG00000158301	ENSG00000168539
Uniprot IDs		B3KW05 Q96D09	P11229 Q53XZ3
PDB IDs			5CXV 6OIJ
Enriched GO Terms of Interacting Partners?
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