HOMER1 and C19orf57

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HOMER1	C19orf57
Description		homer scaffold protein 1	chromosome 19 open reading frame 57
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Z Disc Cell Junction Axon Dendrite Neuron Projection Costamere Dendritic Spine Neuron Spine Apical Part Of Cell Glutamatergic Synapse Postsynaptic Cytosol	Cellular_component
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Signaling Adaptor Activity Ion Channel Binding	Molecular_function Protein Binding
	Biological Process	Skeletal Muscle Contraction Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Positive Regulation Of Signal Transduction Behavioral Response To Cocaine Skeletal Muscle Fiber Development Chemical Homeostasis Within A Tissue Protein Tetramerization Response To Calcium Ion Positive Regulation Of Calcium Ion Transport Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Calcium Ion Import Regulation Of Postsynaptic Neurotransmitter Receptor Activity Regulation Of Dendritic Spine Maintenance Regulation Of Store-operated Calcium Entry Regulation Of Cation Channel Activity	Multicellular Organism Development
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Blood and toenail selenium levels ( 25343990) Height ( 18193045) Hepcidin/ferritin ratio ( 27846281) Lateral ventricle temporal horn volume ( 31530798) Major depressive disorder ( 20673876) Metabolite levels ( 23823483) Toenail selenium levels ( 25343990)
Interacting Genes		20 interacting genes: ABI3 AGAP2 C19orf57 C1orf116 DBNL DNM3 EFNB2 FAT1 GRIA1 GRIK1 GRM1 GRM5 HOMER3 ITPR1 RYR1 RYR2 SHANK1 STX12 TANC1 TRPC1	27 interacting genes: AIMP2 AKAP8L APP C19orf25 CENPQ COPS4 CTNNAL1 EWSR1 FAM9B FBXO25 GDF15 GPS2 HAUS3 HOMER1 IKBKG KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 PSMA6 RABL6 RUNX1T1 STXBP1 TRIM23 TSC22D3 VCL
Entrez ID		9456	79173
HPRD ID		09211	14415
Ensembl ID		ENSG00000152413	ENSG00000132016
Uniprot IDs		Q5U5K4 Q86YM7	Q0VDD7
PDB IDs
Enriched GO Terms of Interacting Partners?
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