HOMER1 and FAT1

Number of citations of the paper that reports this interaction (PubMedID 16979624)
11

Data Source:
HPRD (in vitro)

		HOMER1	FAT1
Description		homer scaffold protein 1	FAT atypical cadherin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Z Disc Cell Junction Axon Dendrite Neuron Projection Costamere Dendritic Spine Neuron Spine Apical Part Of Cell Glutamatergic Synapse Postsynaptic Cytosol	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Signaling Adaptor Activity Ion Channel Binding	Calcium Ion Binding Protein Binding
	Biological Process	Skeletal Muscle Contraction Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Positive Regulation Of Signal Transduction Behavioral Response To Cocaine Skeletal Muscle Fiber Development Chemical Homeostasis Within A Tissue Protein Tetramerization Response To Calcium Ion Positive Regulation Of Calcium Ion Transport Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Calcium Ion Import Regulation Of Postsynaptic Neurotransmitter Receptor Activity Regulation Of Dendritic Spine Maintenance Regulation Of Store-operated Calcium Entry Regulation Of Cation Channel Activity	Epithelial Cell Morphogenesis Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Cell Migration Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Camera-type Eye Morphogenesis Cell-cell Adhesion
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Blood and toenail selenium levels ( 25343990) Height ( 18193045) Hepcidin/ferritin ratio ( 27846281) Lateral ventricle temporal horn volume ( 31530798) Major depressive disorder ( 20673876) Metabolite levels ( 23823483) Toenail selenium levels ( 25343990)	Alzheimer disease and age of onset ( 26830138) Carotid plaque burden ( 28282560) Chronotype ( 26955885) Heel bone mineral density ( 30598549) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (calcium channel blockers) ( 31015401) Morning vs. evening chronotype ( 26955885) Obesity ( 21552555) PR interval ( 30046033) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		20 interacting genes: ABI3 AGAP2 C19orf57 C1orf116 DBNL DNM3 EFNB2 FAT1 GRIA1 GRIK1 GRM1 GRM5 HOMER3 ITPR1 RYR1 RYR2 SHANK1 STX12 TANC1 TRPC1	12 interacting genes: CLK1 ENAH HOMER1 HOMER3 IGLL1 MT-ND1 NOXA1 SORBS2 TRAF4 TRIM14 UBC VASP
Entrez ID		9456	2195
HPRD ID		09211	02986
Ensembl ID		ENSG00000152413	ENSG00000083857
Uniprot IDs		Q5U5K4 Q86YM7	Q14517
PDB IDs
Enriched GO Terms of Interacting Partners?
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