ITM2B and KASH5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ITM2B	KASH5
Description		integral membrane protein 2B	KASH domain containing 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Endosome Membrane Membrane Golgi-associated Vesicle Membrane Integral Component Of Organelle Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Chromosome, Telomeric Region Lateral Element Cell Nuclear Outer Membrane Integral Component Of Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Meiotic Spindle Pole
	Molecular Function	Amyloid-beta Binding Protein Binding ATP Binding	Protein Binding Identical Protein Binding Dynein Complex Binding
	Biological Process	Nervous System Development Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Cellular Protein Metabolic Process	Double-strand Break Repair Via Homologous Recombination Actin Filament Organization Synapsis Spermatogenesis Telomere Localization Oogenesis Spindle Assembly Spindle Localization Microtubule Cytoskeleton Organization Involved In Homologous Chromosome Segregation Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: APP BCL2 CREB3 KASH5 LMNA NAALADL2 SYNE4	76 interacting genes: ABHD1 ADIPOQ ATF7 BAG5 BCL2L2 BET1 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CRABP2 CXCL16 CXCL9 CYBC1 EMD FAM161A FAM90A1 FATE1 FIS1 FRA10AC1 FTCD GABARAPL2 GALNT2 GOSR2 GPATCH4 GPR25 HMOX1 ITM2B JAGN1 KDM1A LARP1 LAT LENG1 LHFPL5 LMNA MALL MARCHF2 MFSD5 MMP14 MS4A1 MTX2 NRIP3 NSG1 NTAQ1 OLFM4 PDGFRA PLP2 PPP1R18 RIPPLY2 RNF146 RSRC2 RTP2 SENP2 SERP2 SGTA SHMT2 SLC30A2 SLC41A2 SLN SMCO4 STBD1 STX5 TCF25 TMEM11 TMEM14C TMEM199 TMEM41A TMPRSS4 TRAF3IP3 TSHZ3 UPK1B UPK2 VAMP1 VAMP4 ZNF250
Entrez ID		9445	147872
HPRD ID		04878	08134
Ensembl ID		ENSG00000136156	ENSG00000161609
Uniprot IDs		A0A384MDP7 Q9Y287	Q8N6L0
PDB IDs
Enriched GO Terms of Interacting Partners?
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