KASH5 and GALNT2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KASH5	GALNT2
Description		KASH domain containing 5	polypeptide N-acetylgalactosaminyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Lateral Element Cell Nuclear Outer Membrane Integral Component Of Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Meiotic Spindle Pole	Golgi Membrane Extracellular Region Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Membrane Integral Component Of Golgi Membrane Golgi Cisterna Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Dynein Complex Binding	Polypeptide N-acetylgalactosaminyltransferase Activity Protein Binding Manganese Ion Binding Carbohydrate Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Actin Filament Organization Synapsis Spermatogenesis Telomere Localization Oogenesis Spindle Assembly Spindle Localization Microtubule Cytoskeleton Organization Involved In Homologous Chromosome Segregation Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation	Immunoglobulin Biosynthetic Process Protein O-linked Glycosylation O-glycan Processing Protein O-linked Glycosylation Via Serine Protein O-linked Glycosylation Via Threonine
Pathways			COPI-independent Golgi-to-ER retrograde traffic O-linked glycosylation of mucins
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) Carotid intima media thickness ( 26343869) Circulating myeloperoxidase levels (serum) ( 23620142) Coronary artery disease ( 29212778) Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) Fibrinogen levels ( 28107422) HDL cholesterol ( 24097068 18193043 18193044 20864672 19060906 30275531 25961943 20686565) HDL cholesterol levels ( 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Hematology traits ( 23303382) High density lipoprotein cholesterol levels ( 29403010) Intake of sweets ( 31005972) Metabolic syndrome ( 22399527 31589552) Metabolite levels ( 22916037) Metabolite levels (lipoprotein measures) ( 27005778) Platelet count ( 27863252) Postburn scar pliability ( 30595539) Red cell distribution width ( 27863252 28957414) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels ( 28334899 29403010 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068 18193043 18193044 30275531 25961943 20686565)
Interacting Genes		76 interacting genes: ABHD1 ADIPOQ ATF7 BAG5 BCL2L2 BET1 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CRABP2 CXCL16 CXCL9 CYBC1 EMD FAM161A FAM90A1 FATE1 FIS1 FRA10AC1 FTCD GABARAPL2 GALNT2 GOSR2 GPATCH4 GPR25 HMOX1 ITM2B JAGN1 KDM1A LARP1 LAT LENG1 LHFPL5 LMNA MALL MARCHF2 MFSD5 MMP14 MS4A1 MTX2 NRIP3 NSG1 NTAQ1 OLFM4 PDGFRA PLP2 PPP1R18 RIPPLY2 RNF146 RSRC2 RTP2 SENP2 SERP2 SGTA SHMT2 SLC30A2 SLC41A2 SLN SMCO4 STBD1 STX5 TCF25 TMEM11 TMEM14C TMEM199 TMEM41A TMPRSS4 TRAF3IP3 TSHZ3 UPK1B UPK2 VAMP1 VAMP4 ZNF250	3 interacting genes: KASH5 LMNA MUC1
Entrez ID		147872	2590
HPRD ID		08134	03782
Ensembl ID		ENSG00000161609	ENSG00000143641
Uniprot IDs		Q8N6L0	A0A1L7NY50 B7Z6K2 G3V1S6 Q10471
PDB IDs			2FFU 2FFV 4D0T 4D0Z 4D11 5AJN 5AJO 5AJP 5FV9 5NDF 6EGS
Enriched GO Terms of Interacting Partners?
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