KASH5 and VAMP4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KASH5	VAMP4
Description		KASH domain containing 5	vesicle associated membrane protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Lateral Element Cell Nuclear Outer Membrane Integral Component Of Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Meiotic Spindle Pole	Golgi Membrane Lysosome Endosome Golgi Apparatus Plasma Membrane Cell Surface Transport Vesicle Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Identical Protein Binding Dynein Complex Binding	Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Actin Filament Organization Synapsis Spermatogenesis Telomere Localization Oogenesis Spindle Assembly Spindle Localization Microtubule Cytoskeleton Organization Involved In Homologous Chromosome Segregation Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation	Microtubule Cytoskeleton Organization ER To Golgi Vesicle-mediated Transport Synaptic Vesicle To Endosome Fusion SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Membrane Organization Golgi Ribbon Formation Regulation Of Synaptic Vesicle Endocytosis
Pathways			Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal atrophy ( 25625606) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		76 interacting genes: ABHD1 ADIPOQ ATF7 BAG5 BCL2L2 BET1 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CRABP2 CXCL16 CXCL9 CYBC1 EMD FAM161A FAM90A1 FATE1 FIS1 FRA10AC1 FTCD GABARAPL2 GALNT2 GOSR2 GPATCH4 GPR25 HMOX1 ITM2B JAGN1 KDM1A LARP1 LAT LENG1 LHFPL5 LMNA MALL MARCHF2 MFSD5 MMP14 MS4A1 MTX2 NRIP3 NSG1 NTAQ1 OLFM4 PDGFRA PLP2 PPP1R18 RIPPLY2 RNF146 RSRC2 RTP2 SENP2 SERP2 SGTA SHMT2 SLC30A2 SLC41A2 SLN SMCO4 STBD1 STX5 TCF25 TMEM11 TMEM14C TMEM199 TMEM41A TMPRSS4 TRAF3IP3 TSHZ3 UPK1B UPK2 VAMP1 VAMP4 ZNF250	11 interacting genes: AP1M1 BCL2L13 CSNK2A1 DNAJC5 KASH5 LMNA PACS1 SNAP29 STX16 STX4 STX6
Entrez ID		147872	8674
HPRD ID		08134	06070
Ensembl ID		ENSG00000161609	ENSG00000117533
Uniprot IDs		Q8N6L0	O75379 Q6IAZ3
PDB IDs
Enriched GO Terms of Interacting Partners?
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