TP53INP1 and MAP1LC3A

Number of citations of the paper that reports this interaction (PubMedID 22421968)
46

Data Source:
BioGRID (fluorescent resonance energy transfer)

		TP53INP1	MAP1LC3A
Description		tumor protein p53 inducible nuclear protein 1	microtubule associated protein 1 light chain 3 alpha
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Autophagosome Cytosol PML Body Cytoplasmic Vesicle	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse
	Molecular Function	Protein Binding Antioxidant Activity	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding
	Biological Process	Autophagosome Assembly Apoptotic Process Cell Cycle Arrest Negative Regulation Of Cell Proliferation Response To Heat Positive Regulation Of Autophagy Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Cellular Response To UV Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Autophagic Cell Death Negative Regulation Of Fibroblast Proliferation Cellular Response To Ethanol Cellular Response To Hydroperoxide Cellular Response To Methyl Methanesulfonate Cellular Oxidant Detoxification Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Myofibroblast Differentiation	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Regulation of TP53 Activity through Phosphorylation	Macroautophagy Pink/Parkin Mediated Mitophagy Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Alzheimer's disease ( 31473137) Intraocular pressure ( 29617998) Macular thickness ( 30535121) Serum uric acid levels ( 30993211 29403010) Type 2 diabetes ( 22885922 24509480 30054458 30297969 20581827 28869590) Urate levels ( 31578528)	Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241)
Interacting Genes		6 interacting genes: GABARAP GABARAPL2 HIPK2 MAP1LC3A SQSTM1 TP53	49 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG101 ATG13 ATG4B BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 KIF15 KXD1 LMNB1 MAP1A MAP1S MDM2 MEFV NBR1 NEDD4 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RB1CC1 RDH12 RETREG3 RTKN SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TUBA4A ULK1
Entrez ID		94241	84557
HPRD ID		09367	03144
Ensembl ID		ENSG00000164938	ENSG00000101460
Uniprot IDs		A0A024R9C8 Q96A56	Q9H492
PDB IDs			3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR
Enriched GO Terms of Interacting Partners?
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