MAP1LC3A and AKAP13

Number of citations of the paper that reports this interaction (PubMedID 19696020)
11

Data Source:
BioGRID (pull down)

		MAP1LC3A	AKAP13
Description		microtubule associated protein 1 light chain 3 alpha	A-kinase anchoring protein 13
Image
GO Annotations	Cellular Component	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse	Nucleus Cytosol Actin Filament Cell Cortex Membrane Cortical Actin Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding	CAMP-dependent Protein Kinase Activity MAP-kinase Scaffold Activity Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rho GTPase Binding Metal Ion Binding Protein Kinase A Binding Molecular Adaptor Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation	Protein Phosphorylation G Protein-coupled Receptor Signaling Pathway Heart Development Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Regulation Of Small GTPase Mediated Signal Transduction Nuclear Export Cardiac Muscle Cell Differentiation Regulation Of Sarcomere Organization Bone Development Cell Growth Involved In Cardiac Muscle Cell Development Adrenergic Receptor Signaling Pathway Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of Glucocorticoid Mediated Signaling Pathway
Pathways		Macroautophagy Pink/Parkin Mediated Mitophagy Receptor Mediated Mitophagy	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241)	Birth weight ( 31043758) Central corneal thickness ( 31798171 29760442 20719862) Corneal structure ( 23291589) Coronary artery disease ( 29212778) Granulocyte percentage of myeloid white cells ( 27863252) Idiopathic pulmonary fibrosis ( 29066090) Intraocular pressure ( 29617998) Mean corpuscular volume ( 27863252) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758) Psoriasis ( 25939698) Pulse pressure ( 30578418) Response to platinum-based chemotherapy (carboplatin) ( 21844884) Systolic blood pressure ( 30578418)
Interacting Genes		49 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG101 ATG13 ATG4B BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 KIF15 KXD1 LMNB1 MAP1A MAP1S MDM2 MEFV NBR1 NEDD4 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RB1CC1 RDH12 RETREG3 RTKN SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TUBA4A ULK1	22 interacting genes: APP CTNNAL1 ESR1 ESR2 GNA12 GNAQ LINC00839 MAP1LC3A PPARA PRKACA PRKAR2A PRKD1 RANBP2 RHOA RTKN RXRB SRPK2 THRA YWHAB YWHAE YWHAG YWHAZ
Entrez ID		84557	11214
HPRD ID		03144	05253
Ensembl ID		ENSG00000101460	ENSG00000170776
Uniprot IDs		Q9H492	A8MYJ1 B0AZU4 Q12802
PDB IDs		3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR	2DRN 2LG1 4D0N 4D0O 6BCA
Enriched GO Terms of Interacting Partners?
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