MAP1LC3A and TBC1D17

Number of citations of the paper that reports this interaction (PubMedID 22354992)
74

Data Source:
BioGRID (pull down)

		MAP1LC3A	TBC1D17
Description		microtubule associated protein 1 light chain 3 alpha	TBC1 domain family member 17
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse	Autophagosome Cytosol Recycling Endosome
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding	GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation	Intracellular Protein Transport Autophagy Retrograde Transport, Endosome To Golgi Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Macroautophagy Pink/Parkin Mediated Mitophagy Receptor Mediated Mitophagy	TBC/RABGAPs
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241)
Interacting Genes		49 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG101 ATG13 ATG4B BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 KIF15 KXD1 LMNB1 MAP1A MAP1S MDM2 MEFV NBR1 NEDD4 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RB1CC1 RDH12 RETREG3 RTKN SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TUBA4A ULK1	19 interacting genes: ASCC2 CALCOCO1 CCT5 CDKN2D DHX29 FBL GABARAPL1 GPS1 GTF3C1 MAP1LC3A MAP1LC3B NIPSNAP1 OPTN RAB1A RAB5A RAB5B RAB5C SLC1A5 TAX1BP1
Entrez ID		84557	79735
HPRD ID		03144	15471
Ensembl ID		ENSG00000101460	ENSG00000104946
Uniprot IDs		Q9H492	Q9HA65
PDB IDs		3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR
Enriched GO Terms of Interacting Partners?
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