COX5A and EPM2A

Number of citations of the paper that reports this interaction (PubMedID 26493215)
5

Data Source:
BioGRID (two hybrid)

		COX5A	EPM2A
Description		cytochrome c oxidase subunit 5A	EPM2A glucan phosphatase, laforin
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GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex IV	Nucleus
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Electron Transfer Activity Metal Ion Binding	Protein Binding
	Biological Process	Mitochondrial Electron Transport, Cytochrome C To Oxygen Proton Transmembrane Transport	Positive Regulation Of Macroautophagy Negative Regulation Of TOR Signaling
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport	Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs		Cholic Acid N-Formylmethionine
Diseases			Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS		Caffeine consumption ( 21490707) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Loneliness (multivariate analysis) ( 27629369) Mean platelet volume ( 27863252) Methadone dose in opioid dependence ( 28115739) Response to mepolizumab in severe asthma ( 29229094)
Interacting Genes		7 interacting genes: COPS6 EPM2A EXOSC8 HTRA1 KRT31 KRT40 MT-CO1	16 interacting genes: COX5A EIF2B1 EPM2AIP1 HMGXB4 NFU1 NHLRC1 PKM PPP1R3C PPP1R3D PRKAA1 PRKAA2 PRKAB2 PSMC3 SRPK2 TDG TOPORS
Entrez ID		9377	7957
HPRD ID		04799	06345
Ensembl ID		ENSG00000178741	ENSG00000112425
Uniprot IDs		P20674	H0UI04 O95278
PDB IDs		5Z62	4R30 4RKK
Enriched GO Terms of Interacting Partners?
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