EPM2A and TOPORS

  • Number of citations of the paper that reports this interaction (PubMedID 26493215)
  • 5
  • Data Source:
  • BioGRID (two hybrid)

EPM2A

TOPORS

Description EPM2A glucan phosphatase, laforin TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Loneliness (multivariate analysis) ( 27629369)
  • Mean platelet volume ( 27863252)
  • Methadone dose in opioid dependence ( 28115739)
  • Response to mepolizumab in severe asthma ( 29229094)
  • Early spontaneous preterm birth ( 31194736)
  • Immune response to smallpox vaccine (IL-6) ( 22610502)
  • Metabolite levels ( 23823483)
Interacting Genes 16 interacting genes: COX5A EIF2B1 EPM2AIP1 HMGXB4 NFU1 NHLRC1 PKM PPP1R3C PPP1R3D PRKAA1 PRKAA2 PRKAB2 PSMC3 SRPK2 TDG TOPORS 28 interacting genes: CASP8 CREBBP EPM2A H2AX HABP4 MTDH NKX3-1 SATB1 SERBP1 SIN3A SNIP1 SPOP SUMO1 SUMO2 TOP1 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2I UBE2J1 UBE2L6 UBE2N UBE2W XRCC1
Entrez ID 7957 10210
HPRD ID 06345 11642
Ensembl ID ENSG00000112425 ENSG00000197579
Uniprot IDs H0UI04 O95278 Q9NS56
PDB IDs 4R30 4RKK
Enriched GO Terms of Interacting Partners?
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