EPM2A and EPM2AIP1

Number of citations of the paper that reports this interaction (PubMedID 12782127)
8

Data Source:
HPRD (in vivo)

		EPM2A	EPM2AIP1
Description		EPM2A glucan phosphatase, laforin	EPM2A interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Cytoplasmic Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Macroautophagy Negative Regulation Of TOR Signaling	Response To Insulin Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glycogen (starch) Synthase Activity
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs
Diseases		Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS		Loneliness (multivariate analysis) ( 27629369) Mean platelet volume ( 27863252) Methadone dose in opioid dependence ( 28115739) Response to mepolizumab in severe asthma ( 29229094)	Autism spectrum disorder or schizophrenia ( 28540026) Subjective response to lithium treatment ( 26503763)
Interacting Genes		16 interacting genes: COX5A EIF2B1 EPM2AIP1 HMGXB4 NFU1 NHLRC1 PKM PPP1R3C PPP1R3D PRKAA1 PRKAA2 PRKAB2 PSMC3 SRPK2 TDG TOPORS	17 interacting genes: ACTN1 C1orf50 CCNB1IP1 CPSF7 EMP2 EPM2A FHL3 KCTD1 MEOX2 MX1 PRTFDC1 REL SERPINF1 TNFAIP1 TRIM54 VPS52 ZBTB14
Entrez ID		7957	9852
HPRD ID		06345	07445
Ensembl ID		ENSG00000112425	ENSG00000178567
Uniprot IDs		H0UI04 O95278	Q7L775
PDB IDs		4R30 4RKK
Enriched GO Terms of Interacting Partners?
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