MAPK1IP1L and ARHGEF16

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		MAPK1IP1L	ARHGEF16
Description		mitogen-activated protein kinase 1 interacting protein 1 like	Rho guanine nucleotide exchange factor 16
Image		No pdb structure
GO Annotations	Cellular Component		Cytosol
	Molecular Function	Protein Binding	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rho GTPase Binding PDZ Domain Binding Receptor Tyrosine Kinase Binding Cadherin Binding
	Biological Process		G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of Small GTPase Mediated Signal Transduction Cell Chemotaxis Activation Of GTPase Activity Positive Regulation Of Protein Localization To Plasma Membrane
Pathways			NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)	Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Response to statin therapy ( 20339536)
Interacting Genes		16 interacting genes: ARHGEF16 C1orf94 CEP55 EIF3E EWSR1 HGS HNRNPUL1 LENG8 PDCD6 RBFOX2 SS18L1 SUMO1 SUMO1P1 TFG UBE2I VPS37C	5 interacting genes: LMNA LNX1 MAPK1IP1L TFG YWHAQ
Entrez ID		93487	27237
HPRD ID		12647	12478
Ensembl ID		ENSG00000168175	ENSG00000130762
Uniprot IDs		Q8NDC0	B3KTS4 Q5VV41
PDB IDs			1X6B
Enriched GO Terms of Interacting Partners?
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