MAPK1IP1L and EIF3E

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		MAPK1IP1L	EIF3E
Description		mitogen-activated protein kinase 1 interacting protein 1 like	eukaryotic translation initiation factor 3 subunit E
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex PML Body Eukaryotic 48S Preinitiation Complex Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3e
	Molecular Function	Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Cadherin Binding Protein N-terminus Binding
	Biological Process		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation Positive Regulation Of Translation Negative Regulation Of Translational Initiation Positive Regulation Of MRNA Binding
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)	Coffee consumption ( 31046077) Dupuytren's disease ( 28886342 21732829) Heel bone mineral density ( 30598549) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)
Interacting Genes		16 interacting genes: ARHGEF16 C1orf94 CEP55 EIF3E EWSR1 HGS HNRNPUL1 LENG8 PDCD6 RBFOX2 SS18L1 SUMO1 SUMO1P1 TFG UBE2I VPS37C	25 interacting genes: ATM C4orf19 COPS6 COPS7A COPS7B COPS8 DDX24 EIF3C EIF3L EIF4ENIF1 EPAS1 GPAA1 GPBP1L1 HAP1 IFIT1 MAPK1IP1L NDRG1 NSF PRRC2A RUNDC3A SHBG SMAD9 TRIM27 TRIM55 TRIM63
Entrez ID		93487	3646
HPRD ID		12647	03734
Ensembl ID		ENSG00000168175	ENSG00000104408
Uniprot IDs		Q8NDC0	P60228
PDB IDs			3J8B 3J8C 6FEC
Enriched GO Terms of Interacting Partners?
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