ARHGEF16 and TFG

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ARHGEF16	TFG
Description		Rho guanine nucleotide exchange factor 16	trafficking from ER to golgi regulator
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rho GTPase Binding PDZ Domain Binding Receptor Tyrosine Kinase Binding Cadherin Binding	Protein Binding Identical Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of Small GTPase Mediated Signal Transduction Cell Chemotaxis Activation Of GTPase Activity Positive Regulation Of Protein Localization To Plasma Membrane	ER To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	COPII-mediated vesicle transport
Drugs
Diseases			Non-small cell lung cancer Thyroid cancer
GWAS		Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Response to statin therapy ( 20339536)
Interacting Genes		5 interacting genes: LMNA LNX1 MAPK1IP1L TFG YWHAQ	32 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL CEP126 CEP55 CRMP1 CSTF2 ERG28 EWSR1 GBP2 GPRASP1 GRB2 HGS HNRNPF MAGED1 MAPK1IP1L MED21 MYOT PEF1 PIN1 PLSCR1 PTPN6 RBPMS RIPPLY2 SEC24A SPG21 STAT5B TOMM70 TRIM25 TSSK2 VPS37C
Entrez ID		27237	10342
HPRD ID		12478	03932
Ensembl ID		ENSG00000130762	ENSG00000114354
Uniprot IDs		B3KTS4 Q5VV41	Q05BK6 Q92734
PDB IDs		1X6B
Enriched GO Terms of Interacting Partners?
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