SNAP29 and STX6

Number of citations of the paper that reports this interaction (PubMedID 26186194)
367

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		SNAP29	STX6
Description		synaptosome associated protein 29	syntaxin 6
Image
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cell Nucleoplasm Cytoplasm Autophagosome Centrosome Cytosol Plasma Membrane Ciliary Pocket Membrane SNARE Complex Azurophil Granule Membrane Presynapse	Golgi Membrane Nucleoplasm Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Clathrin-coated Vesicle Integral Component Of Synaptic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Exocytosis Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Cilium Assembly Membrane Fusion Autophagosome Maturation	Intracellular Protein Transport Vesicle Fusion Endosome Organization Synaptic Vesicle To Endosome Fusion Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking Golgi Ribbon Formation Regulation Of Cellular Protein Localization
Pathways		Neutrophil degranulation Intra-Golgi traffic	Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases		Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS			Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 30089514 21685912)
Interacting Genes		22 interacting genes: AP2A1 ATF4 CD7 DNAJC5 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 RASSF7 STX12 STX17 STX1A STX3 STX4 STX6 STX7 VAMP1 VAMP2 VAMP4 VAMP7	15 interacting genes: DNAJC5 EEA1 GOPC LMNA MARCHF2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX7 VAMP4 VPS11 VPS18
Entrez ID		9342	10228
HPRD ID		11968	07231
Ensembl ID		ENSG00000099940	ENSG00000135823
Uniprot IDs		O95721	O43752
PDB IDs		4WY4	2NPS 4J2C
Enriched GO Terms of Interacting Partners?
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