TRIP10 and ARHGAP12

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIP10	ARHGAP12
Description		thyroid hormone receptor interactor 10	Rho GTPase activating protein 12
Image			No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Nucleoplasm Cytoplasm Lysosome Golgi Apparatus Cytosol Cytoskeleton Cell Cortex Cell Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome	Phagocytic Cup Cytoplasm Cytosol
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	GTPase Activator Activity
	Biological Process	Endocytosis Cell Communication Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Membrane Organization	Morphogenesis Of An Epithelial Sheet Phagocytosis, Engulfment Actin Filament Organization Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle Clathrin-mediated endocytosis	Rho GTPase cycle
Drugs
Diseases
GWAS			C-reactive protein levels ( 24763700) Glycine levels ( 30837465) Intraocular pressure ( 31959993) Pulse pressure ( 28135244 27841878) Systolic blood pressure ( 27841878) Uterine fibroids ( 31649266)
Interacting Genes		28 interacting genes: ABL2 AKAP9 ARHGAP12 ARHGAP17 CDC42 CREBBP CTNNB1 DNM2 HTT LYN PDE6G POT1 PRKACA RHOJ RHOQ RXRA SH3BP1 SMARCE1 SMURF1 SRC STAT3 TERF1 THRB TINF2 WAS WASF1 WASL WBP11	3 interacting genes: SRPK1 SRPK2 TRIP10
Entrez ID		9322	94134
HPRD ID		05142	06446
Ensembl ID		ENSG00000125733	ENSG00000165322
Uniprot IDs		Q15642 W4VSQ9	Q1RLN5 Q8IWW6
PDB IDs		2CT4 2EFK 2KE4
Enriched GO Terms of Interacting Partners?
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