TRIP10 and ABL2

Number of citations of the paper that reports this interaction (PubMedID 18330356)
6

Data Source:
BioGRID (two hybrid)

		TRIP10	ABL2
Description		thyroid hormone receptor interactor 10	ABL proto-oncogene 2, non-receptor tyrosine kinase
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GO Annotations	Cellular Component	Phagocytic Cup Nucleoplasm Cytoplasm Lysosome Golgi Apparatus Cytosol Cytoskeleton Cell Cortex Cell Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome	Cell Cytosol Actin Cytoskeleton
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	Magnesium Ion Binding Phosphotyrosine Residue Binding Actin Monomer Binding Protein Kinase Activity Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Manganese Ion Binding Actin Filament Binding
	Biological Process	Endocytosis Cell Communication Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Membrane Organization	Cellular Protein Modification Process Cell Adhesion Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Autophagy Positive Regulation Of Phospholipase C Activity Positive Regulation Of Neuron Projection Development Peptidyl-tyrosine Phosphorylation Regulation Of Endocytosis Regulation Of Cell Adhesion Negative Regulation Of Rho Protein Signal Transduction Exploration Behavior Regulation Of Apoptotic Process Positive Regulation Of Oxidoreductase Activity Cellular Response To Retinoic Acid Regulation Of Cell Motility Regulation Of Actin Cytoskeleton Reorganization
Pathways		Rho GTPase cycle Clathrin-mediated endocytosis	Role of ABL in ROBO-SLIT signaling Role of ABL in ROBO-SLIT signaling
Drugs			ATP Dasatinib XL228 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE
Diseases
GWAS			IgE grass sensitization ( 22036096)
Interacting Genes		28 interacting genes: ABL2 AKAP9 ARHGAP12 ARHGAP17 CDC42 CREBBP CTNNB1 DNM2 HTT LYN PDE6G POT1 PRKACA RHOJ RHOQ RXRA SH3BP1 SMARCE1 SMURF1 SRC STAT3 TERF1 THRB TINF2 WAS WASF1 WASL WBP11	29 interacting genes: ABL1 BCR C15orf48 CAT CRK DOK1 EGFR EPHB2 ERBB2 ERBB3 ERBB4 FBXO38 GPX1 GRB2 HCK MAP3K10 MDM2 NEDD4 NEDD4L OIP5 PDGFRB PIK3R3 PSMA7 RIN1 SIVA1 SORBS2 STAT3 TPD52L1 TRIP10
Entrez ID		9322	27
HPRD ID		05142	01259
Ensembl ID		ENSG00000125733	ENSG00000143322
Uniprot IDs		Q15642 W4VSQ9	P42684
PDB IDs		2CT4 2EFK 2KE4	2ECD 2KK1 2XYN 3GVU 3HMI 3ULR 4EIH 5NP3 5NP5
Enriched GO Terms of Interacting Partners?
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