TRIP10 and SH3BP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIP10	SH3BP1
Description		thyroid hormone receptor interactor 10	SH3 domain binding protein 1
Image
GO Annotations	Cellular Component	Phagocytic Cup Nucleoplasm Cytoplasm Lysosome Golgi Apparatus Cytosol Cytoskeleton Cell Cortex Cell Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome	Exocyst Phagocytic Cup Intracellular Nucleus Cytosol Adherens Junction Bicellular Tight Junction Lamellipodium Cell Leading Edge
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	GTPase Activator Activity Protein Binding SH3 Domain Binding Semaphorin Receptor Binding Rac GTPase Binding
	Biological Process	Endocytosis Cell Communication Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Membrane Organization	Phagocytosis, Engulfment Actin Filament Organization Cell Migration Regulation Of Actin Filament Depolymerization Regulation Of Actin Cytoskeleton Organization Cell Junction Assembly Regulation Of Rac Protein Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of GTPase Activity Establishment Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Small GTPase Mediated Signal Transduction Semaphorin-plexin Signaling Pathway
Pathways		Rho GTPase cycle Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Interacting Genes		28 interacting genes: ABL2 AKAP9 ARHGAP12 ARHGAP17 CDC42 CREBBP CTNNB1 DNM2 HTT LYN PDE6G POT1 PRKACA RHOJ RHOQ RXRA SH3BP1 SMARCE1 SMURF1 SRC STAT3 TERF1 THRB TINF2 WAS WASF1 WASL WBP11	12 interacting genes: ABL1 CRK HCK NGLY1 POT1 RAC1 RHOA SRC SUN2 SYNJ1 TERF1 TRIP10
Entrez ID		9322	23616
HPRD ID		05142	10227
Ensembl ID		ENSG00000125733	ENSG00000100092
Uniprot IDs		Q15642 W4VSQ9	A0A2X0SFX7 Q9Y3L3
PDB IDs		2CT4 2EFK 2KE4	4J9D 4J9F
Enriched GO Terms of Interacting Partners?
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