KHDRBS2 and HBZ

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KHDRBS2	HBZ
Description		KH RNA binding domain containing, signal transduction associated 2	hemoglobin subunit zeta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Hemoglobin Complex Haptoglobin-hemoglobin Complex Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding Identical Protein Binding	Peroxidase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding Organic Acid Binding
	Biological Process	MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome	Negative Regulation Of Transcription By RNA Polymerase II Oxygen Transport Hydrogen Peroxide Catabolic Process Erythrocyte Maturation Cellular Oxidant Detoxification
Pathways		PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)	Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Early cardiac repolarization ( 31600170) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 29403010)
Interacting Genes		34 interacting genes: AEN CATSPER1 CHTOP CIRBP DOCK2 EWSR1 GRAP2 GRB2 HBZ HNRNPK HNRNPLL KHDRBS3 LINC01018 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBM10 RBM3 RBMX SDCBP SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF688	15 interacting genes: APP DOCK8 FGFR3 HBB HBD HNRNPD IKBKG KHDRBS2 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 NOTCH2NLA SP1 UPF2
Entrez ID		202559	3050
HPRD ID		13775	00794
Ensembl ID		ENSG00000112232	ENSG00000130656
Uniprot IDs		Q5VWX1	P02008
PDB IDs			1JEB 3W4U
Enriched GO Terms of Interacting Partners?
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