ACY3 and ASPA

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		ACY3	ASPA
Description		aminoacylase 3	aspartoacylase
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Apical Plasma Membrane Extracellular Exosome	Nucleus Cytosol
	Molecular Function	Molecular_function Aminoacylase Activity Protein Binding Hydrolase Activity, Acting On Ester Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Identical Protein Binding Metal Ion Binding	Aminoacylase Activity Protein Binding Hydrolase Activity, Acting On Ester Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Aspartoacylase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Xenobiotic Metabolic Process Biological_process Viral Process	Aspartate Catabolic Process Cellular Amino Acid Biosynthetic Process Central Nervous System Myelination Positive Regulation Of Oligodendrocyte Differentiation
Pathways		Aflatoxin activation and detoxification	Aspartate and asparagine metabolism
Drugs		L-Aspartic Acid	L-Aspartic Acid Zinc
Diseases			Canavan disease (CD)
GWAS		Serum metabolite levels ( 24625756) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)	Myopia (pathological) ( 23049088)
Interacting Genes		14 interacting genes: AAMDC ASPA GORASP2 KRTAP10-3 KRTAP10-8 LNX1 MAP3K8 NEDD4L NOTCH2NLA PIAS2 PLEKHF2 PMM2 RARG RRAS	2 interacting genes: ACY3 ZYG11B
Entrez ID		91703	443
HPRD ID		12422	02033
Ensembl ID		ENSG00000132744	ENSG00000108381
Uniprot IDs		A0A024R5L2 Q96HD9	P45381 Q6FH48
PDB IDs			2I3C 2O4H 2O53 2Q51 4MRI 4MXU 4NFR 4TNU
Enriched GO Terms of Interacting Partners?
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