ASPA and ACY3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		ASPA	ACY3
Description		aspartoacylase	aminoacylase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Cytosol Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Aminoacylase Activity Protein Binding Hydrolase Activity, Acting On Ester Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Aspartoacylase Activity Identical Protein Binding Metal Ion Binding	Molecular_function Aminoacylase Activity Protein Binding Hydrolase Activity, Acting On Ester Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Identical Protein Binding Metal Ion Binding
	Biological Process	Aspartate Catabolic Process Cellular Amino Acid Biosynthetic Process Central Nervous System Myelination Positive Regulation Of Oligodendrocyte Differentiation	Xenobiotic Metabolic Process Biological_process Viral Process
Pathways		Aspartate and asparagine metabolism	Aflatoxin activation and detoxification
Drugs		L-Aspartic Acid Zinc	L-Aspartic Acid
Diseases		Canavan disease (CD)
GWAS		Myopia (pathological) ( 23049088)	Serum metabolite levels ( 24625756) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		2 interacting genes: ACY3 ZYG11B	14 interacting genes: AAMDC ASPA GORASP2 KRTAP10-3 KRTAP10-8 LNX1 MAP3K8 NEDD4L NOTCH2NLA PIAS2 PLEKHF2 PMM2 RARG RRAS
Entrez ID		443	91703
HPRD ID		02033	12422
Ensembl ID		ENSG00000108381	ENSG00000132744
Uniprot IDs		P45381 Q6FH48	A0A024R5L2 Q96HD9
PDB IDs		2I3C 2O4H 2O53 2Q51 4MRI 4MXU 4NFR 4TNU
Enriched GO Terms of Interacting Partners?
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