CD3E and NCK1

  • Number of citations of the paper that reports this interaction (PubMedID 12110186)
  • 128
  • Data Source:
  • HPRD (two hybrid, in vivo, in vitro)

CD3E

NCK1

Description CD3e molecule NCK adaptor protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199)
  • Blood urea nitrogen levels ( 31152163)
  • Body mass index ( 25673413)
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 20 interacting genes: CD3D CD3EAP CD3G CD79B CSK EPS8L1 LCK NCK1 NCK2 NCL PIK3R1 PTPN22 SHC1 SNTA1 SYK TOP2B TRAT1 TRB UNC119 ZAP70 86 interacting genes: ABI1 ABI2 ABL1 ADAM15 ADGRL2 ARHGAP32 ARHGEF7 BCAR1 BLNK BRK1 CAV2 CBL CBLB CD3E CRK CSNK1G2 CYFIP2 DAG1 DCC DNM1 DOK1 DOK2 DRD3 DRD4 EFS EGFR EIF2B2 EIF2S2 EPHB1 EPHB2 ERBB3 FASLG FCHO1 FGFR1 FLT1 FLT3 FRS2 GAB2 GMPPA HOMEZ KDR KHDRBS1 KIAA1522 LCP2 MAP4K1 MAP4K4 MINK1 NCKAP1 NCKAP5 NCKIPSD NEDD9 NPHS1 NTRK2 NUTM2F OLIG1 PAK1 PAK2 PAK3 PDGFRB PFN1 PHC2 PIK3R3 PKN2 PLCG1 PTK2 PXN RAC1 RASA1 RHOU RRAS SH2D1A SHANK3 SOCS1 SOCS7 SORBS3 SOS1 SYNJ2 SYNPO TBK1 TNIK TNK2 UBA52 WAS WASF1 WASL WIPF1
Entrez ID 916 4690
HPRD ID 08923 02740
Ensembl ID ENSG00000198851 ENSG00000158092
Uniprot IDs P07766 A0A0S2Z4Y3 P16333
PDB IDs 1A81 1SY6 1XIW 2ROL 6JXR 2CI8 2CI9 2CUB 2JS0 2JS2 2JW4
Enriched GO Terms of Interacting Partners?
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