PDLIM1 and SUPT4H1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		PDLIM1	SUPT4H1
Description		PDZ and LIM domain 1	SPT4 homolog, DSIF elongation factor subunit
Image
GO Annotations	Cellular Component	Stress Fiber Transcription Factor Complex Adherens Junction Focal Adhesion Z Disc Filamentous Actin	Nucleus Nucleoplasm DSIF Complex
	Molecular Function	Transcription Coactivator Activity Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding Cadherin Binding Involved In Cell-cell Adhesion	RNA Polymerase II Complex Binding DNA-binding Transcription Factor Activity Single-stranded RNA Binding Protein Binding Zinc Ion Binding Protein Heterodimerization Activity
	Biological Process	Response To Hypoxia Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Heart Development Actin Cytoskeleton Organization Muscle Structure Development Cell-cell Adhesion Positive Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Mean platelet volume ( 27863252) Suicide risk ( 21041247)	Mental health study participation (completed survey) ( 31263887)
Interacting Genes		13 interacting genes: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 RLIM RPS6KA5 STK35 SUPT4H1 VIM	11 interacting genes: ANXA5 APP EWSR1 HTATSF1 LRIF1 LRRK2 MFHAS1 NSG2 PDLIM1 SUPT5H XRCC5
Entrez ID		9124	6827
HPRD ID		09326	16026
Ensembl ID		ENSG00000107438	ENSG00000213246
Uniprot IDs		O00151 V9HW92	P63272
PDB IDs		1X62 2PKT	3H7H 5OIK 6GMH 6GML
Enriched GO Terms of Interacting Partners?
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