PDLIM1 and GFAP

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PDLIM1	GFAP
Description		PDZ and LIM domain 1	glial fibrillary acidic protein
Image
GO Annotations	Cellular Component	Stress Fiber Transcription Factor Complex Adherens Junction Focal Adhesion Z Disc Filamentous Actin	Cytoplasm Lysosome Cytosol Intermediate Filament Intermediate Filament Cytoskeleton
	Molecular Function	Transcription Coactivator Activity Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding Cadherin Binding Involved In Cell-cell Adhesion	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding
	Biological Process	Response To Hypoxia Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Heart Development Actin Cytoskeleton Organization Muscle Structure Development Cell-cell Adhesion Positive Regulation Of Nucleic Acid-templated Transcription	Regulation Of Protein Complex Assembly Intermediate Filament Organization Regulation Of Chaperone-mediated Autophagy
Pathways			Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases			Alexander disease
GWAS		Mean platelet volume ( 27863252) Suicide risk ( 21041247)	Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)
Interacting Genes		13 interacting genes: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 RLIM RPS6KA5 STK35 SUPT4H1 VIM	51 interacting genes: AKT1 APP AURKB BIRC2 CAMK2A CDK1 CEP76 CFAP206 CRYAB FAM50B GOLGA2 GRAP2 HGS IKBKG KIAA0408 KRT13 KRT15 KRT19 LGALS14 LMO2 MEN1 MOS MYO15B NEFL NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCB1 SRC STAT1 TLE5 TRIM27 TUBGCP4 UBE3A VIM ZC2HC1C
Entrez ID		9124	2670
HPRD ID		09326	00675
Ensembl ID		ENSG00000107438	ENSG00000131095
Uniprot IDs		O00151 V9HW92	A7REI1 P14136
PDB IDs		1X62 2PKT	6A9P
Enriched GO Terms of Interacting Partners?
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