SUPT4H1 and PDLIM1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		SUPT4H1	PDLIM1
Description		SPT4 homolog, DSIF elongation factor subunit	PDZ and LIM domain 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm DSIF Complex	Stress Fiber Transcription Factor Complex Adherens Junction Focal Adhesion Z Disc Filamentous Actin
	Molecular Function	RNA Polymerase II Complex Binding DNA-binding Transcription Factor Activity Single-stranded RNA Binding Protein Binding Zinc Ion Binding Protein Heterodimerization Activity	Transcription Coactivator Activity Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription	Response To Hypoxia Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Heart Development Actin Cytoskeleton Organization Muscle Structure Development Cell-cell Adhesion Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Mental health study participation (completed survey) ( 31263887)	Mean platelet volume ( 27863252) Suicide risk ( 21041247)
Interacting Genes		11 interacting genes: ANXA5 APP EWSR1 HTATSF1 LRIF1 LRRK2 MFHAS1 NSG2 PDLIM1 SUPT5H XRCC5	13 interacting genes: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 RLIM RPS6KA5 STK35 SUPT4H1 VIM
Entrez ID		6827	9124
HPRD ID		16026	09326
Ensembl ID		ENSG00000213246	ENSG00000107438
Uniprot IDs		P63272	O00151 V9HW92
PDB IDs		3H7H 5OIK 6GMH 6GML	1X62 2PKT
Enriched GO Terms of Interacting Partners?
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