RGN and NR1D2

Number of citations of the paper that reports this interaction (PubMedID 15604093)
54

Data Source:
HPRD (two hybrid)

		RGN	NR1D2
Description		regucalcin	nuclear receptor subfamily 1 group D member 2
Image
GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Cytosol	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	Gluconolactonase Activity Calcium Ion Binding Zinc Ion Binding Enzyme Regulator Activity	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity Signaling Receptor Activity Transcription Factor Activity, Direct Ligand Regulated Sequence-specific DNA Binding
	Biological Process	Kidney Development Negative Regulation Of Protein Kinase Activity Cellular Calcium Ion Homeostasis Spermatogenesis Aging Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Phosphatase Activity L-ascorbic Acid Biosynthetic Process Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of ATPase Activity Negative Regulation Of GTPase Activity Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Negative Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of Epithelial Cell Proliferation Regulation Of Calcium-mediated Signaling Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Liver Regeneration Negative Regulation Of Flagellated Sperm Motility Positive Regulation Of Superoxide Dismutase Activity Positive Regulation Of Calcium-transporting ATPase Activity Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Bone Development Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Calcium-dependent ATPase Activity Negative Regulation Of DNA Catabolic Process Positive Regulation Of DUTP Diphosphatase Activity Negative Regulation Of Leucine-tRNA Ligase Activity Negative Regulation Of DNA Biosynthetic Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Multicellular Organism Development Hormone-mediated Signaling Pathway Regulation Of Lipid Metabolic Process Cell Differentiation Intracellular Receptor Signaling Pathway Response To Lipid Regulation Of Circadian Rhythm Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Circadian Behavior Regulation Of Inflammatory Response Negative Regulation Of Inflammatory Response Lipid Homeostasis Energy Homeostasis Regulation Of Skeletal Muscle Cell Differentiation
Pathways			Nuclear Receptor transcription pathway
Drugs		Calcium Citrate Calcium Phosphate
Diseases
GWAS			Acne (severe) ( 24927181) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Asthma ( 29273806) Cognitive ability ( 29186694) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: NR1D2 THRA	24 interacting genes: CRY1 CSNK1E CSNK2A2 CUL1 DELEC1 GTF2B HDAC1 KRT40 KRTAP10-9 KRTAP4-2 MID2 NCOA5 NCOR1 NOTCH2NLA NR1D1 PRMT6 RBPMS RGN RORC SIN3B TAF6 TAF9 TRIM27 UBE2I
Entrez ID		9104	9975
HPRD ID		02196	03809
Ensembl ID		ENSG00000130988	ENSG00000174738
Uniprot IDs		Q15493 V9HWF8	B4DXD3 F1D8P2 Q14995
PDB IDs		3G4E 3G4H 4GNB 4GNC	2V0V 2V7C 3CQV 4N73
Enriched GO Terms of Interacting Partners?
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