AEN and HOMEZ

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AEN	HOMEZ
Description		apoptosis enhancing nuclease	homeobox and leucine zipper encoding
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Nucleic Acid Binding Exonuclease Activity Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity
	Biological Process	DNA Catabolic Process, Exonucleolytic RNA Catabolic Process Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Viral Genome Replication Defense Response To Virus	Negative Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)	Height ( 31562340) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		34 interacting genes: CRTC3 EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473	37 interacting genes: AEN AXIN1 CENPS DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 ELOA GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK1 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPGR RPL9 SDCBP SH3RF2 SMARCB1 SMYD1 SNRPB2 SUMO2 TEAD4 TLE5 TRAF4 ZBTB7A ZNF688
Entrez ID		64782	57594
HPRD ID		08573	12167
Ensembl ID		ENSG00000181026	ENSG00000215271
Uniprot IDs		Q8WTP8	Q8IX15
PDB IDs			2ECC 2YS9
Enriched GO Terms of Interacting Partners?
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