PSTPIP1 and PTPN18

Number of citations of the paper that reports this interaction (PubMedID 11971877)
79

Data Source:
HPRD (in vivo)

		PSTPIP1	PTPN18
Description		proline-serine-threonine phosphatase interacting protein 1	protein tyrosine phosphatase non-receptor type 18
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GO Annotations	Cellular Component	Uropod Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Identical Protein Binding	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Innate Immune Response	Blastocyst Formation Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation ERBB2 Signaling Pathway Cellular Response To Cytokine Stimulus Negative Regulation Of ERBB Signaling Pathway
Pathways		The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection	Downregulation of ERBB2 signaling Interleukin-37 signaling
Drugs
Diseases		Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS		Neurofibrillary tangles ( 31497858)
Interacting Genes		42 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 DNM2 EXOC5 FAM90A1 FASLG FBXL18 HMG20A KHDRBS1 LSM4 MEFV MFGE8 MVP NAV2 PCDHB14 PRPF31 PTPN12 PTPN18 RINT1 RTP5 RXRB SDCBP SH2D4A SHBG SPG7 SYCE1 TFIP11 TRAF3IP3 TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZNF175 ZNF688	11 interacting genes: AATK ABL1 ARHGAP5 CSK EGFR ERBB2 GAB1 PSTPIP1 PSTPIP2 SRC TEC
Entrez ID		9051	26469
HPRD ID		05891	05961
Ensembl ID		ENSG00000140368	ENSG00000072135
Uniprot IDs		A0A0S2Z5P3 O43586	Q99952
PDB IDs		2DIL	2OC3 4GFU 4GFV 4NND
Enriched GO Terms of Interacting Partners?
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