PSTPIP1 and LSM4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PSTPIP1	LSM4
Description		proline-serine-threonine phosphatase interacting protein 1	LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
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GO Annotations	Cellular Component	Uropod Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm	P-body Nucleus Nucleoplasm U6 SnRNP Cytosol Membrane Protein-containing Complex Neuron Projection U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Identical Protein Binding	RNA Binding Protein Binding U6 SnRNA Binding PH Domain Binding
	Biological Process	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Innate Immune Response	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways		The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases		Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS		Neurofibrillary tangles ( 31497858)	Chronotype ( 30696823) Estimated glomerular filtration rate ( 30604766) Gastroesophageal reflux disease ( 31527586) Intraocular pressure ( 29617998) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252)
Interacting Genes		42 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 DNM2 EXOC5 FAM90A1 FASLG FBXL18 HMG20A KHDRBS1 LSM4 MEFV MFGE8 MVP NAV2 PCDHB14 PRPF31 PTPN12 PTPN18 RINT1 RTP5 RXRB SDCBP SH2D4A SHBG SPG7 SYCE1 TFIP11 TRAF3IP3 TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZNF175 ZNF688	19 interacting genes: CALCOCO2 COX5B IKZF1 L3MBTL3 LSM1 LSM7 NMI PLEKHA5 PSTPIP1 RHOXF2 SLC22A2 SMIM14 SMN1 SMU1 SNRPE TOE1 TOP1 XRN1 ZBTB10
Entrez ID		9051	25804
HPRD ID		05891	06284
Ensembl ID		ENSG00000140368	ENSG00000130520
Uniprot IDs		A0A0S2Z5P3 O43586	Q9Y4Z0 U3KQK1
PDB IDs		2DIL	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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