IFT20 and EMILIN1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		IFT20	EMILIN1
Description		intraflagellar transport 20	elastin microfibril interfacer 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Photoreceptor Outer Segment Golgi Apparatus Cis-Golgi Network Centrosome Centriole Microvillus Cilium Intraciliary Transport Particle B Motile Cilium Photoreceptor Connecting Cilium Stereocilium Dendrite Terminus Ciliary Tip Ciliary Base Kinociliary Basal Body	Extracellular Region Collagen Trimer Extracellular Space Integrin Alpha4-beta1 Complex Collagen-containing Extracellular Matrix Extracellular Exosome EMILIN Complex
	Molecular Function	Opsin Binding Protein Binding Rab GTPase Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Identical Protein Binding Integrin Binding Involved In Cell-matrix Adhesion
	Biological Process	Establishment Of Planar Polarity Kidney Development Smoothened Signaling Pathway Spermatogenesis Visual Learning Protein Localization To Golgi Apparatus Intraciliary Transport Involved In Cilium Assembly Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Establishment Of Epithelial Cell Apical/basal Polarity Centrosome Localization Cardiac Muscle Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Protein Localization To Plasma Membrane Cochlea Development Regulation Of Cilium Assembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Autophagosome Assembly	Aortic Valve Morphogenesis Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Collagen Biosynthetic Process Elastic Fiber Assembly Negative Regulation Of Cell Activation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Collagen Fibril Organization Negative Regulation Of Macrophage Migration
Pathways		Intraflagellar transport Intraflagellar transport	Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Osteoprotegerin levels ( 25080503)
Interacting Genes		27 interacting genes: ABI2 BLOC1S6 CROCCP2 DISC1 DTNBP1 EMILIN1 EXOC7 FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KIF3B KPNA2 KRT13 KXD1 NDC80 NUP54 NUP62 PSMA1 PTPN12 TREX1 USHBP1 WASF1 WASHC3 ZDHHC17	15 interacting genes: BEX3 BEX5 COG7 DYNC1I1 EMILIN2 IFT20 LAIR2 MIA2 MTMR9 NECAB2 NMI PLAC9 RIBC1 YJU2 ZC2HC1C
Entrez ID		90410	11117
HPRD ID		17137	00563
Ensembl ID		ENSG00000109083	ENSG00000138080
Uniprot IDs		A0A024QZ08 A0A087X2B4 Q8IY31	Q9Y6C2
PDB IDs			2KA3 2OII
Enriched GO Terms of Interacting Partners?
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