EMILIN1 and ZC2HC1C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EMILIN1	ZC2HC1C
Description		elastin microfibril interfacer 1	zinc finger C2HC-type containing 1C
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Integrin Alpha4-beta1 Complex Collagen-containing Extracellular Matrix Extracellular Exosome EMILIN Complex
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Identical Protein Binding Integrin Binding Involved In Cell-matrix Adhesion	Protein Binding Metal Ion Binding
	Biological Process	Aortic Valve Morphogenesis Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Collagen Biosynthetic Process Elastic Fiber Assembly Negative Regulation Of Cell Activation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Collagen Fibril Organization Negative Regulation Of Macrophage Migration
Pathways		Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases
GWAS			Neurociticism ( 29500382)
Interacting Genes		15 interacting genes: BEX3 BEX5 COG7 DYNC1I1 EMILIN2 IFT20 LAIR2 MIA2 MTMR9 NECAB2 NMI PLAC9 RIBC1 YJU2 ZC2HC1C	26 interacting genes: ACTN2 BANP CALCOCO2 CBY2 CCDC136 CCDC85B EMILIN1 FBXO7 FSD2 GFAP HOOK2 KRT15 KRT20 KRT40 LMNA MID2 MTUS2 PNMA1 RABGEF1 SFN SPAG5 TFIP11 TRAF1 TRAF2 TRIM23 TRIM27
Entrez ID		11117	79696
HPRD ID		00563	16607
Ensembl ID		ENSG00000138080	ENSG00000119703
Uniprot IDs		Q9Y6C2	A0A024R6E6 J3KMY6 Q53FD0
PDB IDs		2KA3 2OII
Enriched GO Terms of Interacting Partners?
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