EMILIN1 and MTMR9

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		EMILIN1	MTMR9
Description		elastin microfibril interfacer 1	myotubularin related protein 9
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Integrin Alpha4-beta1 Complex Collagen-containing Extracellular Matrix Extracellular Exosome EMILIN Complex	Cytoplasm Endoplasmic Reticulum Cytosol Ruffle Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Identical Protein Binding Integrin Binding Involved In Cell-matrix Adhesion	Protein Binding Protein Phosphatase Binding Enzyme Regulator Activity
	Biological Process	Aortic Valve Morphogenesis Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Collagen Biosynthetic Process Elastic Fiber Assembly Negative Regulation Of Cell Activation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Collagen Fibril Organization Negative Regulation Of Macrophage Migration	Phosphatidylinositol Biosynthetic Process Endocytosis Negative Regulation Of Autophagy Positive Regulation Of Phosphatase Activity Protein Stabilization Regulation Of Phosphatidylinositol Dephosphorylation
Pathways		Molecules associated with elastic fibres Molecules associated with elastic fibres	Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the late endosome membrane Synthesis of IP2, IP, and Ins in the cytosol
Drugs
Diseases
GWAS			Adventurousness ( 30643258) Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463) Extraversion ( 27918536) General factor of neuroticism ( 30867560) Retinal vascular caliber ( 21060863) Systemic lupus erythematosus ( 26316170)
Interacting Genes		15 interacting genes: BEX3 BEX5 COG7 DYNC1I1 EMILIN2 IFT20 LAIR2 MIA2 MTMR9 NECAB2 NMI PLAC9 RIBC1 YJU2 ZC2HC1C	16 interacting genes: AATK EMILIN1 ERBB3 ERBB4 EWSR1 KDM1A LNX1 MOS MTMR6 MTMR7 MTMR8 NMI PTK7 ROR2 SPG21 VAC14
Entrez ID		11117	66036
HPRD ID		00563	09377
Ensembl ID		ENSG00000138080	ENSG00000104643
Uniprot IDs		Q9Y6C2	Q96QG7
PDB IDs		2KA3 2OII
Enriched GO Terms of Interacting Partners?
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