WASL and SNX9

Number of citations of the paper that reports this interaction (PubMedID 18388313)
41

Data Source:
BioGRID (pull down)

		WASL	SNX9
Description		WASP like actin nucleation promoting factor	sorting nexin 9
Image
GO Annotations	Cellular Component	Cell Nucleus Cytosol Actin Filament Plasma Membrane Actin Cytoskeleton Lamellipodium Actin Cap Actin Cortical Patch Endocytic Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome	Ruffle Cytoplasm Trans-Golgi Network Cytosol Plasma Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle Cuticular Plate Extracellular Exosome
	Molecular Function	Protein Binding GTPase Regulator Activity Actin Filament Binding	Protein Binding 1-phosphatidylinositol Binding Ubiquitin Protein Ligase Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Arp2/3 Complex Binding
	Biological Process	Actin Cortical Patch Assembly Endocytosis Vesicle Budding From Membrane Actin Polymerization Or Depolymerization Regulation Of Cell Shape Response To Bacterium Vesicle Organization Actin Filament Polymerization Actin Filament-based Movement Vesicle Transport Along Actin Filament Regulation Of Protein Localization Cellular Protein-containing Complex Localization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Actin Nucleation Cell Division Positive Regulation Of Filopodium Assembly Spindle Localization Actin Cortical Patch Localization Dendritic Spine Morphogenesis Membrane Organization Protein-containing Complex Assembly Negative Regulation Of Membrane Tubulation Positive Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Lymphocyte Migration Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Mitotic Cytokinesis Intracellular Protein Transport Endocytosis Receptor-mediated Endocytosis Endosomal Transport Positive Regulation Of Actin Filament Polymerization Cleavage Furrow Formation Positive Regulation Of GTPase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Membrane Protein Ectodomain Proteolysis Lipid Tube Assembly Membrane Organization Protein-containing Complex Assembly Plasma Membrane Tubulation
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation NOSTRIN mediated eNOS trafficking Nephrin family interactions EPHB-mediated forward signaling EPHB-mediated forward signaling DCC mediated attractive signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	Golgi Associated Vesicle Biogenesis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Platelet count ( 22139419 27863252) Plateletcrit ( 27863252)	Borderline personality disorder ( 28632202) Heart rate response to beta blockers ( 29478026) Lipoprotein (a) - cholesterol levels ( 25575512) Metabolite levels ( 23823483) Platelet distribution width ( 27863252)
Interacting Genes		51 interacting genes: AASS ABL1 ACTG1 ACTR2 ACTR3 APBB1 APP ARPC3 BIN1 CDC42 CORO7 CTTN DNMBP EGFR EVL FCHSD2 FNBP1 FNBP1L GRB2 HP HSP90AA1 HSP90AB1 IPO5 ITSN1 ITSN2 LCK NCK1 NCK2 NCKIPSD PACSIN1 PACSIN2 PACSIN3 PFN1 PRMT2 PRPF40A PSTPIP1 PTK6 RHOJ RHOQ RNF8 RPL7AP66 SDCBP SH3GL3 SNX9 SRC TRIP10 VASP VIPR1 WIPF1 WIPF2 ZNF395	22 interacting genes: ADAM15 ADAM9 CLTC DAPK1 DNM1 DNM2 EGFR FASLG ITCH KHDRBS1 LRRK1 MPHOSPH6 MPP6 PAK2 PI4KA PIK3CA PIK3R5 SOS1 SOS2 TNK2 WAS WASL
Entrez ID		8976	51429
HPRD ID		05448	12072
Ensembl ID		ENSG00000106299	ENSG00000130340
Uniprot IDs		O00401	Q9Y5X1
PDB IDs		2FF3 2LNH 2VCP 4CC2 4CC7	2RAI 2RAJ 2RAK 3DYT 3DYU 3LGE
Enriched GO Terms of Interacting Partners?
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