USP13 and LAPTM5

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USP13	LAPTM5
Description		ubiquitin specific peptidase 13	lysosomal protein transmembrane 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Lysosome Lysosomal Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Proliferation Regulation Of Autophagy Protein Deubiquitination Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway	Cellular Response To Leukemia Inhibitory Factor
Pathways		Ub-specific processing proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS			Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369)
Interacting Genes		23 interacting genes: AMFR BAG6 DVL1 FNBP1L FUNDC2 GPR160 HSP90AA1 LAPTM5 MCL1 MDC1 MRPL20 MYO15A PTEN S100A9 SIAH2 SPRR2C SYCP2 TRA2B TRIM55 TRIM63 UBC UBL4A UIMC1	25 interacting genes: ANKRD13A DCUN1D1 DISP1 EPN1 EPN2 EPN3 EPS15 HERC1 HEY1 HEYL HUWE1 ITCH KRT7 LDLRAD1 NEDD4 NEDD4L RNF168 SMURF2 TNFAIP3 TOM1L2 UBA52 UBAC1 UBC USP13 WWP1
Entrez ID		8975	7805
HPRD ID		04666	03280
Ensembl ID		ENSG00000058056	ENSG00000162511
Uniprot IDs		A0A0A6YZ17 Q92995	Q13571 Q5TBB8
PDB IDs		2L80 2LBC
Enriched GO Terms of Interacting Partners?
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